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My P pulcher spazzes out when I open the lid for maintenance and will bail if I'm not careful. She's not a bad spider, she's just nervous. Nervous can turn bad regardless of species.
My T vagans female surprised me the other day. I'll post about it in her thread but when changing her water dish she launched at it when I was returning it to her enclosure. She has never done that before. It startled me but I was prepared and nothing bad happened except she owned an empty water dish and fanged it for about an hour lol